Completely Delete User Profiles with a Script

Here’s a useful script that will automatically delete ALL user profiles that are on a Windows Server 2008/R2 computer.

WARNING!
This is a dangerous operation, designed for use by an administrator who needs to do a complete purge; for instance at the end of a semester.

Note: 
For purposes of this example, we will use the following path for the script files:
D:\Scripts

• Copy the below provided code into the notepad and save it as delete_profiles.vbs in D:\Scripts 

• Create a new notepad file and copy the following line:

cscript.exe “D:\Scripts\delete_profiles.vbs SRVNAME” > “D:\Scripts\profile_delete.txt”

• Where SRVNAME is the name of the server where you want to delete the profiles.The redirection (>) in that command line acts to create (or append) a text file named profile_delete.txt that will act to log the deletions.

• Save it as delete_all_profiles.bat and save it in D:\Scripts

• Create a scheduled job and run delete_all_profiles.bat at the desired time.
  I suggest using a batch file and setting up a scheduled task as that lets the script run with the necessary permissions.

Here is the code for the script file: delete_profiles.vbs

On Error Resume Next

args = WScript.Arguments.Count

If args <> 1 Then
  WScript.Echo "usage: delete_profiles SVRNAME"
  WScript.Echo "example (for remote profiles): cscript.exe delete_profiles SOMESERVER  "
  WScript.Echo "example (for local profiles): cscript.exe delete_profiles .  "
  WScript.Quit
End If

strComputer = WScript.Arguments.Item(0)
Set objWMIService = GetObject("winmgmts:\\" & strComputer &"\root\cimv2")
Set colProfiles = objWMIService.ExecQuery("Select * from Win32_UserProfile")
Wscript.Echo "==" & WScript.Arguments.Item(0) & "==" & vbNewLine

For Each objProfile in colProfiles
  Set objSID = objWMIService.Get("Win32_SID.SID='" & objProfile.SID &"'")
      If (objSID.ReferencedDomainName = "DOMAIN NAME") Then
      If Not ((objSID.AccountName = "USERNAME TO EXCLUDE") Or (Left (objSID.AccountName,2) = "USERNAME PREFIX TO EXCLUDE")) Then
          Set objUserProfile = GetObject("winmgmts:{impersonationlevel=impersonate}!\\" _
          & strComputer &"\root\cimv2:Win32_UserProfile." _
          &"SID='" & objProfile.Sid &"'")
          objUserProfile.Delete_
     Wscript.Echo objSID.AccountName & ";" & objSID.ReferencedDomainName & ";" & objProfile.LocalPath & " - " & "DELETED"
     End If
End If
Next

NOTES: In line 19 you have to specify the domain name to be used in the script and in line 20 you can specify user accounts that shouldn’t be deleted, like Administrator accounts.

Courtesy: KresimiK